Mexican Cheesy Beef Casserole Recipe: An Easy and Flavorful Dinner

If you’re craving a hearty, cheesy, and flavor-packed dish, this Mexican Cheesy Beef Casserole Recipe is the perfect comfort food! Loaded with seasoned ground beef, melted cheese, beans, and tortilla layers, this casserole is easy to make and perfect for weeknight dinners or feeding a crowd.

With a rich and savory taco-seasoned beef filling combined with layers of gooey cheese and crispy tortillas, this dish delivers bold Mexican flavors in every bite. Plus, it’s easily customizable add your favorite toppings like sour cream, guacamole, salsa, or jalapeños to take it to the next level!

If you’re looking for another delicious, crowd-pleasing casserole, try this Cowboy Casserole Recipe with crispy tater tots and a creamy beef mixture.

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ground beef tortilla casserole

Mexican Cheesy Beef Casserole Recipe

Make this easy Mexican Cheesy Beef Casserole Recipe with layers of seasoned beef, tortillas, and gooey cheese. Perfect for a quick weeknight dinner!
Prep Time 15 minutes
Cook Time 30 minutes
Resting Time 5 minutes
Total Time 50 minutes
Course Dinner, Main Course
Cuisine American, Mexican
Servings 6 to 8 People
Calories 350 kcal

INGREDIENTS
  

For the Beef Mixture:

  • 1 lb ground beef – Lean ground beef 85/15 or 90/10 for best results
  • 1 packet taco seasoning – Or use homemade seasoning mix
  • ½ cup water – To mix with the seasoning
  • 1 small onion diced – Optional, for extra flavor

For the Layers:

  • 6 medium flour tortillas – Soft tortillas for layering or use corn tortillas for a gluten-free option
  • 1 can black beans 15 oz, drained and rinsed
  • 1 cup corn kernels – Fresh frozen, or canned
  • 1 can diced tomatoes with green chilies Rotel, drained

For the Cheese and Sauce:

  • 2 cups shredded Mexican cheese blend – A mix of Monterey Jack cheddar, and queso quesadilla
  • 1 cup salsa or enchilada sauce – For added moisture and flavor
  • ½ cup sour cream – Optional for a creamy layer

INSTRUCTIONS
 

Cook the Beef

  • Heat a large skillet over medium heat. Add diced onion (if using) and sauté for 2–3 minutes.
  • Add 1 lb ground beef and cook until browned, about 5–7 minutes.
  • Drain excess grease and stir in taco seasoning and ½ cup water. Simmer for 2–3 minutes until the mixture thickens.

Prepare the Layers

  • Preheat oven to 350°F (175°C).
  • Grease a 9×13-inch baking dish.
  • Spread ⅓ cup of salsa or enchilada sauce at the bottom.
  • Place 2 tortillas on top, slightly overlapping if necessary.
  • Add half of the beef mixture, followed by:
  • ½ cup black beans
  • ½ cup corn
  • ½ cup diced tomatoes with green chilies
  • ½ cup shredded cheese

Repeat and Top with Cheese

  • Add another layer of 2 tortillas and repeat the filling layers.
  • Finish with a final layer of tortillas, the remaining sauce, and the rest of the cheese.

Bake the Casserole

  • Cover with foil and bake for 20 minutes.
  • Remove foil and bake for another 10 minutes until the cheese is golden and bubbly.

Let It Rest and Serve

  • Allow the casserole to rest for 5 minutes before slicing.
  • Garnish with chopped cilantro, sour cream, diced avocado, or jalapeños.

NOTES

Tips for the Best Casserole
  • Pre-toast tortillas: Lightly toast tortillas in a skillet before layering to prevent sogginess.
  • Drain ingredients properly: Drain the beans, corn, and tomatoes to prevent excess moisture.
  • Add extra flavor: Mix fresh cilantro or chopped jalapeños into the beef mixture for added spice.
  • Cheese variety: For a richer, creamier texture, use a mix of Monterey Jack and Pepper Jack.
 
With these simple steps and helpful tips, you’ll have a flavor-packed, cheesy, and satisfying Mexican Beef Casserole that’s perfect for any occasion!

Ingredients for Mexican Cheesy Beef Casserole Recipe

This Mexican Cheesy Beef Casserole Recipe is a family favorite that’s loaded with layers of seasoned beef, tortillas, melty cheese, and savory beans. It’s easy to customize and perfect for a comforting weeknight meal. Here’s everything you’ll need:

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1. Ground Beef & Seasonings

  • 1 lb ground beef: Lean ground beef works best (85/15 or 90/10)
  • 1 packet taco seasoning: Or use homemade seasoning:
    • 1 tsp chili powder
    • ½ tsp cumin
    • ½ tsp paprika
    • ½ tsp garlic powder
    • ¼ tsp onion powder
    • ¼ tsp salt and black pepper

2. Tortillas or Tortilla Chips

  • 6 medium flour tortillas: Soft and pliable for easy layering
  • Or use corn tortillas for a gluten-free option
  • Tortilla chips: Optional, for extra crunch on top

3. Cheese Blend

  • 2 cups shredded Mexican cheese blend: For a melty, cheesy topping
  • Optional: Add ½ cup Monterey Jack or Pepper Jack for extra creaminess and a hint of spice

4. Beans & Veggies

  • 1 can black beans: Drained and rinsed
  • 1 cup corn kernels: Fresh, frozen, or canned
  • 1 small onion: Finely diced (optional)
  • 1 can diced tomatoes with green chilies: (Rotel) for added flavor

5. Sauce Options

  • 1 cup salsa or enchilada sauce: Adds moisture and flavor to the layers
  • ½ cup sour cream: Optional for a creamy layer between tortillas

6. Garnish & Extras

Diced avocado or pico de gallo: Optional for topping

Chopped cilantro: For freshness

Sour cream or guacamole: For serving

Sliced jalapeños: For extra heat

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For a sweet and savory side, pair this dish with the Din Tai Fung Cucumber Salad for a refreshing contrast.

Step-by-Step Cooking Instructions for Mexican Cheesy Beef Casserole Recipe

Follow these simple steps to make a Mexican Cheesy Beef Casserole Recipe that’s bursting with flavor and topped with gooey melted cheese.

1. Cook the Beef

  • Heat a large skillet over medium heat and add 1 tablespoon of oil.
  • Add 1 small diced onion (if using) and sauté for 2–3 minutes until softened.
  • Add 1 lb ground beef to the skillet and cook for 5–7 minutes, breaking it apart with a spoon, until browned and fully cooked.
  • Drain any excess grease.
  • Stir in 1 packet of taco seasoning and ½ cup water. Simmer for 2–3 minutes until the mixture thickens.

2. Prepare the Layers

  • Preheat oven to 350°F (175°C).
  • Grease a 9×13-inch baking dish to prevent sticking.
  • Spread ⅓ cup of salsa or enchilada sauce on the bottom of the dish.
  • Place 2 tortillas on top, overlapping if needed.
  • Add half of the beef mixture, followed by:
    • ½ cup black beans
    • ½ cup corn kernels
    • ⅓ cup diced tomatoes with green chilies
    • ½ cup shredded cheese

3. Add the Next Layers

  • Add another layer of 2 tortillas and repeat the layering process with the remaining ingredients.
  • Top with the final layer of tortillas, the rest of the salsa or sauce, and the remaining cheese.
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4. Bake the Casserole

  • Cover the baking dish loosely with foil to prevent the cheese from burning.
  • Bake for 20 minutes, then remove the foil.
  • Continue baking for another 10–15 minutes until the cheese is melted and bubbly.

5. Let It Rest & Serve

  • Remove the casserole from the oven and let it rest for 5 minutes to set.
  • Garnish with chopped cilantro, sour cream, jalapeños, or avocado if desired.
  • Slice and serve warm with your favorite toppings.
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Love cheesy dishes? Try this indulgent Tini’s Mac and Cheese for a creamy, cheesy side that pairs perfectly.

Tips for a Perfectly Cheesy Mexican Beef Casserole Recipe

Achieving a crispy, flavorful, and cheesy Mexican Beef Casserole recipe requires a few simple techniques. Follow these tips to ensure your casserole turns out perfectly every time.

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1. Preventing Soggy Tortillas

  • Pre-toast the tortillas: Lightly toast the tortillas in a skillet for 1–2 minutes per side before layering. This helps them hold up better against the sauce.
  • Use less sauce: Avoid overloading the casserole with salsa or enchilada sauce. Too much liquid can make the tortillas soggy.
  • Drain ingredients properly: Make sure to drain the beans, corn, and tomatoes to prevent excess moisture.

2. Adding Extra Flavor

  • Sauté the onions and garlic: Cooking onions and garlic with the beef adds richness and depth to the filling.
  • Mix in fresh herbs: Add chopped cilantro or parsley to the beef mixture or sprinkle on top for added freshness.
  • Add a kick of heat: For a spicier version, mix in chopped jalapeños or a dash of hot sauce to the beef.

3. Choosing the Best Cheese

  • Use a blend of cheeses: A mix of Mexican cheese blend, Monterey Jack, and cheddar gives the perfect melt and flavor.
  • Grate your own cheese: Pre-shredded cheese contains anti-caking agents that can affect the texture. Freshly grated cheese melts smoother.
  • Add extra cheese on top: For a golden, bubbly finish, sprinkle an extra layer of cheese during the last 5 minutes of baking.

4. Layering for Even Cooking

  • Spread ingredients evenly: Ensure each layer is evenly distributed to prevent uneven cooking.
  • Press down gently between layers: Lightly press the layers to help the tortillas absorb the sauce and hold everything together.

5. Let It Rest Before Serving

  • Rest for 5 minutes: Letting the casserole sit after baking allows the layers to set and makes slicing easier.

If you’re a fan of Mexican-inspired dishes, don’t miss this Buldak Ramen Recipe for a spicy, fiery twist on instant noodles.

Tasty Variations and Add-Ins for Mexican Cheesy Beef Casserole Recipe

Customize your Mexican Cheesy Beef Casserole Recipe with these flavorful variations and creative add-ins. Whether you’re craving more heat, a vegetarian option, or extra texture, these ideas will take your casserole to the next level.

1. Spicy Version

Turn up the heat for those who love bold flavors.

  • Add jalapeños or serrano peppers: Finely chop and mix into the beef mixture for an extra kick.
  • Use spicy taco seasoning: Opt for hot taco seasoning or add ½ teaspoon cayenne pepper to the mix.
  • Drizzle with hot sauce: Add a layer of your favorite hot sauce or chipotle sauce before adding the cheese.
  • Top with pepper jack cheese: Swap out the standard cheese blend with spicy pepper jack for extra heat.

2. Vegetarian Option

Easily make this dish meat-free while keeping it delicious and satisfying.

  • Replace ground beef with beans: Use black beans, pinto beans, or a mix for protein and fiber.
  • Add sautéed bell peppers and zucchini: Add more vegetables for flavor and texture.
  • Include mushrooms for a meaty texture: Finely chopped portobello or button mushrooms add depth and heartiness.
  • Use extra cheese for richness: Double the cheese to create a creamy and filling dish.

3. Adding Rice for a Heartier Casserole

Add rice to make the casserole even more filling and satisfying.

  • Mix cooked rice into the beef mixture: Add 1–1½ cups of cooked rice before layering.
  • Use Mexican rice for extra flavor: Opt for seasoned Mexican rice or cilantro-lime rice to complement the dish.
  • Layer rice between tortillas: Create an extra layer of rice between the meat and tortilla layers.

4. Adding Corn for Sweetness and Texture

Corn adds a touch of sweetness and pops of texture to balance the savory flavors.

  • Mix corn into the beef layer: Use 1 cup of fresh, frozen, or canned corn for added flavor.
  • Layer corn between tortillas: Add a layer of corn before the cheese for a sweet crunch.
  • Top with roasted corn for a smoky finish: Sprinkle charred or grilled corn on top before serving.

For a fun variation on a classic dessert, try these Chocolate Peanut Butter Rice Krispie Bars a great post-dinner treat!

Best Toppings and Side Dishes for Mexican Cheesy Beef Casserole Recipe

Complete your Mexican Cheesy Beef Casserole Recipe with the perfect toppings and side dishes to balance the flavors and add variety to your meal. Whether you’re looking for something cool and creamy or fresh and vibrant, these options pair perfectly with your casserole.

1. Best Toppings

Guacamole

  • Creamy and rich with a hint of lime, guacamole adds a refreshing contrast to the spicy, cheesy casserole.
  • For extra flavor, try adding diced tomatoes, jalapeños, and fresh cilantro to your guacamole.
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Salsa

  • Choose from mild, medium, or hot salsa to suit your heat preference.
  • Try pico de gallo for a fresh, chunky option or roasted tomato salsa for a smoky kick.

Sour Cream

  • Adds coolness and balances the spice.
  • For a lighter option, use Greek yogurt as a tangy alternative.

Cilantro

  • Fresh chopped cilantro adds brightness and freshness.
  • Sprinkle generously on top after baking for extra flavor.
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If you’re craving a side dish that complements the casserole, consider this Sausage Quiche Recipe for a hearty, protein-packed option.

2. Best Side Dishes

Mexican Rice

  • A classic side that complements the casserole perfectly.
  • Try cilantro-lime rice for a fresh, zesty twist.

Refried Beans

  • Creamy and savory, refried beans add extra richness.
  • Top with a sprinkle of cheese or a dash of hot sauce for added flavor.

Corn Salad

  • A refreshing, tangy corn salad adds sweetness and crunch.
  • Mix corn with lime juice, cilantro, and cotija cheese for a vibrant side.

Tortilla Chips and Queso

  • Crispy chips with warm, melty queso make a great starter or side.
  • Use them to scoop up extra sauce or toppings from the casserole.

Grilled Vegetables

  • Charred bell peppers, zucchini, and onions add smoky flavor.
  • Drizzle with olive oil and lime juice for extra brightness.

3. Drinks to Pair with Your Casserole

  • Horchata: A sweet, cinnamon-flavored rice milk drink.
  • Margaritas: Classic lime margaritas add a refreshing citrus balance.
  • Agua Fresca: Light, fruit-infused water to cool down spicy bites.

How to Store and Reheat Leftovers

To keep your Mexican Cheesy Beef Casserole Recipe fresh and flavorful, follow these simple storage and reheating tips.

1. Storing Leftovers

  • Refrigerate: Let the casserole cool completely before storing. Place leftovers in an airtight container or cover the baking dish tightly with foil or plastic wrap. It will stay fresh in the refrigerator for up to 3–4 days.
  • Freeze for Longer Storage:
    • Allow the casserole to cool completely.
    • Wrap individual portions or the entire dish in plastic wrap and foil to prevent freezer burn.
    • Freeze for up to 2 months.
    • Thaw overnight in the refrigerator before reheating.

2. Best Reheating Methods

Oven (Best for Crispy Top)

  • Preheat oven to 350°F (175°C).
  • Cover the casserole with foil to prevent drying out.
  • Bake for 15–20 minutes until heated through.
  • For extra crispiness, remove foil during the last 5 minutes.

Microwave (Quick Option)

  • Place a portion of the casserole on a microwave-safe plate.
  • Heat on medium power for 1–2 minutes.
  • Stir or rotate halfway through for even heating.

Air Fryer (For Crispy Edges)

  • Preheat air fryer to 350°F (175°C).
  • Place individual portions in the air fryer basket.
  • Heat for 5–7 minutes, checking for even warmth.

FAQs About Mexican Cheesy Beef Casserole Recipe

1. Can I Make It Ahead of Time?

Yes! This casserole is perfect for making ahead:

  • Assemble the casserole: Follow all steps up to baking. Cover tightly and refrigerate for up to 24 hours before baking.
  • Bake when ready: Add an extra 5–10 minutes to the baking time if baking straight from the fridge.
  • Freeze before baking: Assemble, cover tightly, and freeze for up to 2 months. Thaw in the fridge overnight and bake as directed.

2. What’s the Best Cheese to Use?

For the best melt and flavor:

  • Mexican cheese blend: A mix of cheddar, Monterey Jack, and queso quesadilla gives a melty and flavorful result.
  • Monterey Jack or Pepper Jack: Adds creaminess and a mild kick.
  • Cheddar: Provides a sharper, more robust flavor.

For a golden, bubbly finish, grate your own cheese instead of using pre-shredded cheese, which contains anti-caking agents that can affect melting.

3. How Do I Make It Gluten-Free?

To make this casserole gluten-free:

  • Use corn tortillas instead of flour tortillas. They provide a slightly different texture but hold up well.
  • Check taco seasoning: Some pre-packaged taco seasonings may contain gluten. Opt for a gluten-free taco seasoning mix or make your own with chili powder, cumin, paprika, and garlic powder.
  • Verify canned ingredients: Make sure the diced tomatoes, enchilada sauce, and beans are labeled gluten-free.

Conclusion

Mexican Cheesy Beef Casserole Recipe is a hearty, satisfying dish that’s easy to customize and perfect for feeding a crowd. Whether you prefer a mild, classic version or a spicy, bold twist, this casserole is sure to be a hit with family and friends.

Now that you have all the tips and tricks, it’s time to get cooking and enjoy this cheesy, comforting casserole!

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